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transheterozygosity
Friday 20 January 2006
For example, in ADPKD (autosomal dominant polycystic kidney disease), if the germline mutation involves the gene PKD1, the second hit might occur in PKD1 but also in PKD2, or vice versa, so creating a transheterozygote.
See also
homozygosity heterozygosity compound heterozygosity