Home > G. Tumoral pathology > Molecular pathology of tumors > Genetic anomalies > Cancer cytogenetics > Tumoral translocations > t(11;18)(q21;q21)
t(11;18)(q21;q21)
Friday 9 December 2005
BIRC3 at 11q21 and MALT1 at 18q21
Molecular biology
BIRC3-MALT1 fusion transcript (API2-MALT1)
Tumors
B-cell lymphomas
- marginal zone B-cell lymphomas of mucosa-associated lymphoid tissues (MALTs) (50%-60%)
References
Wang G, Auerbach A, Wei M, Dow N, Barry TS, Hodge L, Schaffer D, Sobin LH, Aguilera NS. t(11;18)(q21;q21) in extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue in stomach: a study of 48 cases. Mod Pathol. 2008 Sep 26. PMID: 18820661
Suguro-Katayama M, Suzuki R, Kasugai Y, Nakamura T, Suzuki H, Hosokawa Y, Shiku H, Nakamura S, Seto M. Heterogeneous copy numbers of API2-MALT1 chimeric transcripts in mucosa-associated lymphoid tissue lymphoma. Leukemia. 2003 Dec;17(12):2508-12. PMID: 14562112