Home > G. Tumoral pathology > Molecular pathology of tumors > Genetic anomalies > LOH by regions > 1p36 LOH
1p36 LOH
Saturday 18 June 2005
Tumors
neuroblastomas (1p36.3 LOH) (25%)
gliomas
- oligodendroglioma
- astrocytomas
pheochromocytomas (67%)
paragangliomas (50%)
hepatocellular carcinoma
Candidate genes
PRDM2 (RIZ1)
SHREW1
KCNAB2
CHD5
CAMTA1 (17222547)
FLJ10737 (17222547)
ARID1A (17492758)
Subregions
1p36.11 LOH
1p36.3 LOH
References
1p36 tumor suppression—a matter of dosage? Henrich KO, Schwab M, Westermann F. Cancer Res. 2012 Dec 1;72(23):6079-88. doi : 10.1158/0008-5472.CAN-12-2230 PMID: 23172308