Home > G. Tumoral pathology > Molecular pathology of tumors > Genetic anomalies > LOH by regions > 22q11 LOH
22q11 LOH
Monday 19 May 2008
Tumors
meningiomas (18474292)
Target genes
BCR (breakpoint cluster region)
RAB36 (a member of RAS oncogene family)
GNAZ [guanine nucleotide binding protein (G protein), alpha-z polypeptide]
RTDR1 (rhabdoid tumor deletion region gene 1)
References
Wozniak K, Piaskowski S, Gresner SM, Golanska E, Bieniek E, Bigoszewska K, Sikorska B, Szybka M, Kulczycka-Wojdala D, Zakrzewska M, Zawlik I, Papierz W, Stawski R, Jaskolski DJ, Och W, Sieruta M, Liberski PP, Rieske P. BCR expression is decreased in meningiomas showing loss of heterozygosity of 22q within a new minimal deletion region. Cancer Genet Cytogenet. 2008 May;183(1):14-20. PMID: 18474292