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trisomy 2

Tumors

- isolated (trisomy 2 as the sole chromosomal abnormality)

  • hepatoblastomas (#1377013#)
    • trisomy 2-associated hepatoblastoma
  • myelodysplastic syndrome transforming to acute myeloblastic leukemia and chronic myelomonocytic leukemia (#12885468#)

- associated

  • hepatoblastomas (#11150606#, #10565309#, #9546070#, #8908169#, #7809507#, #1377013#)
  • embryonal rhabdomyosarcoma
  • pleuropulmonary blastoma (pulmonary blastoma of childhood)
  • PTLDs (#16337866#)

See also

- tumoral trisomies

References

- Czepulkowski B, Saunders K, Pocock C, Sadullah S. Mosaic trisomy 2 in myelodysplastic syndromes and acute myeloblastic leukemias. Cancer Genet Cytogenet. 2003 Aug;145(1):78-81. PMID: #12885468#

- Bardi G, Johansson B, Pandis N, Heim S, Mandahl N, Bekassy A, Hagerstrand I, Mitelman F. Trisomy 2 as the sole chromosomal abnormality in a hepatoblastoma. Genes Chromosomes Cancer. 1992 Jan;4(1):78-80. PMID: #1377013#