Abnormalities of the cytoskeleton underlie a variety of pathologic states.
The normal cytoskeleton
The cytoskeleton consists of microtubules (20 to 25 nm in diameter), thin actin filaments (6 to 8 nm), thick myosin filaments (15 nm), and various classes of intermediate filaments (10 nm). Several other nonpolymerized and nonfilamentous forms of contractile proteins also exist.
Cytoskeletal abnormalities may be reflected by: (1) defects in cell function, such as cell locomotion and (...)
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Cellular lesions
Cellular lesions
Articles
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cytoskeletal anomalies
4 February 2006 -
pseudo-Gaucher cell
29 December 2006pseudo-Gaucher histiocytes, pseudo-Gaucher macrophages
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foamy macrophages in the spleen
20 July 2007Etiology
infections mycobacterioses Mycobacterium avium intracellulare infection (MAI infection) (Case 12002)
metabolic diseases storage diseases
Case records
Case 12002 : Systemic granulomatosis in Mycobacterium avium intracellulare
See also
medullary macrophages
splenic macrophages -
rhabdomyocytic lesions
28 May 2007Types (Examples)
rhabdomyocytic steatosis
See also
Myocytes rhabdomyocytes -
syncitial cells
18 March 2007Digital slides
JRC:14069 : Lung metastasis of a choriocarcinoma from mediastinum.
Examples
normal tissue syncytiotrophoblast
lesional conditions giant cell transformations of hepatocytes
syncitial cell tumors choriocarcinoma
See also
syncitium -
hepatocytic PAS+ non-glycogenic globules
12 March 2007Periodic acid Schiff-positive non-glycogenic globules in hepatocytes
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lipofuscin deposits in intestinal smooth muscle cells
8 January 2006See also
lipofuscin deposits
intestinal smooth muscle cells -
intramacrophagic crystals
2 December 2005 -
deposits in smooth muscle cells
8 January 2006Types (Exemples)
lipofuscin deposits in smooth muscle cells
See also
Smooth muscle smooth muscle cells -
intramacrophagic cholesterol crystals
3 December 2005cholesterol crystals in macrophages