hepatocytic PAS+ non-glycogenic globules

Loacalization

 centrilobular regions (362805)

• non-alpha-1-antitrypsin globules
  • centrilobular sinusoidal dilatation (362805)
  • confluent centrilobular necrosis (362805)
  • hepatic congestion (2451899)

 periportal regions

• alpha-1-antitrypsin globules

Types

 hepatocytic alpha-1-antitrypsin globules

References

 Reintoft I. Periodic acid Schiff-positive non-glycogenic globules in hepatocytes. Differential diagnostic aspects in screening for alpha-1-antitrypsin globules in an autopsy material. Acta Pathol Microbiol Scand [A]. 1978 Jul;86(4):325-9. PMID: 362805

 Qizilbash A, Young-Pong O. Alpha 1 antitrypsin liver disease differential diagnosis of PAS-positive, diastase-resistant globules in liver cells. m J Clin Pathol. 1983 Jun;79(6):697-702. PMID: 189389

 att EC, Koss MN, Young TS, Macauley L, Martin SE. Hepatic hyaline globules associated with passive congestion. Arch Pathol Lab Med. 1988 May;112(5):510-3. PMID: 2451899

 Pariente EA, Degott C, Martin JP, Feldmann G, Potet F, Benhamou JP. Hepatocytic PAS-positive diastase-resistance inclusions in the absence of alpha-1-antitrypsin deficiency—high prevalence in alcoholic cirrhosis. Am J Clin Pathol. 1981 Sep;76(3):299-302. PMID: 6169273