nodal lymphoid depletion

Definition : Nodal lymphoid depletion or atrophy is the sequela to chronic necrosis or apoptosis. It can occur in any lymph node and there can be differences in the presence and severity of lymphoid depletion between lymph nodes in the same animal.

Lymphoid depletion is typically characterized by a decrease in the number and size of follicles with few to no germinal centers and/or depletion of paracortical lymphocytes.

With a depletion of paracortical lymphocytes, the stromal cells and vessels may become more prominent.

See also

 nodal anomalies
 lymphoid depletion