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salivary oncocytosis

Sunday 2 September 2012

Nodular oncocytic hyperplasia

Nodular oncocytic hyperplasia (oncocytosis) of the salivary glands is a benign process that does not inherently require surgical excision.

Although oncocytosis demonstrates some overlap with Warthin tumor and oncocytoma, it lacks the diagnostic findings specific to oncocytic salivary gland tumors such as salivary duct carcinoma , acinic cell carcinoma , mammary analog secretory carcinoma , and mucoepidermoid carcinoma.

Despite current limitations in the understanding of oncocytic salivary gland lesions, the presence of a paucicellular specimen comprised of small groups of oncocytic cells should raise the possibility of oncocytosis in the differential diagnosis and can favor it in elderly patients with multiple salivary nodules.

Digital case

 JRC:18973 : Oncocytic nodular hyperplasia in Warthin tumor with a discussion of oncocytoma and diffuse oncocytosis ( M / Age: 79.00 / Organ: Left parotid gland).