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RNA study from fine-needle aspiration
Monday 5 December 2011
FNAC, obtained either by cytoaspirator or syringe and needle, is a good source of small amounts of RNA.
Microarray technology provides a new opportunity to improve the diagnostic accuracy of fine needle aspiration (FNA) in evaluating thyroid nodules. FNA is a reliable alternative to tissue samples in predicting malignancy with microarray. (20186006)
References
Comparative expression of a set of genes to an internal housekeeping control in CDNA amplified and not amplified by PolyAPCR in non-Hodgkin’s lymphoma samples obtained from fine-needle aspiration cytology. Corbi FC, Inaoka RJ, Felix RS, Andrade VC, Etto LY, Vettore AL, Franco MF, Colleoni GW. Diagn Mol Pathol. 2010 Mar;19(1):40-4. PMID: 20186011
Comparison of microarray analysis of fine needle aspirates and tissue specimen in thyroid nodule diagnosis. Kundel A, Zarnegar R, Kato M, Moo TA, Zhu B, Scognamiglio T, Fahey TJ 3rd. Diagn Mol Pathol. 2010 Mar;19(1):9-14. PMID: 20186006