Evolutionary genetics

• neutral theory of molecular evolution
  30 January 2006

  According to the neutral theory of molecular evolution, some classes of mutation have too small an effect on fitness to be affected by natural selection.
  References
  Chamary JV, Parmley JL, Hurst LD. Hearing silence: non-neutral evolution at synonymous sites in mammals. Nat Rev Genet. 2006 Feb;7(2):98-108. PMID: #16418745#

• developmental evolution
  18 January 2006

  References
  Alonso CR, Wilkins AS. Opinion: the molecular elements that underlie developmental evolution. Nat Rev Genet. 2005 Sep;6(9):709-15. PMID: #16094311#

• natural selection
  26 January 2005

  The process by which individuals’ inherited needs and abilities are more or less closely matched to resources available in their environment, giving those with greater "fitness" a better chance of survival and reproduction.
  Charles Darwin’s theory of biological evolution, based on the survival and replication of the fittest and most adaptable genes, through competition over limited natural resources.
  References
  Jensen JD, Wong A, Aquadro CF. Approaches for identifying targets of positive (...)

• evolutionary genomics
  26 January 2005

  Yeasts (#20559329#)
  genome sequences have become available from an increasing range of yeast species, which has led to notable advances in our understanding of evolutionary mechanisms in eukaryotes.
  Yeasts offer us a unique opportunity to examine how molecular and reproductive mechanisms combine to affect genome architectures and drive evolutionary changes over a broad range of species.
  Several molecular mechanisms - such as gene duplication, mutation and acquisition of novel genetic (...)

• evolution
  25 November 2003

  Examples
  molecular evolution
  cellular evolution
  tissular evolution
  organ evolution
  organism evolution / speciation / species
  References
  Dean AM, Thornton JW. Mechanistic approaches to the study of evolution: the functional synthesis. Nat Rev Genet. 2007 Sep;8(9):675-88. PMID: #17703238#
  Mitchell-Olds T, Willis JH, Goldstein DB. Which evolutionary processes influence natural genetic variation for phenotypic traits? Nat Rev Genet. 2007 Nov;8(11):845-56. PMID: #17943192#
  Müller (...)

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