MALT lymphoma

Digital cases

 HPC:296 : Colonic MALT lymphoma
 HPC:303 - Pulmonary plasmocytic MALT lymphoma / pulmonary plasmocytic marginal zone lymphoma
 HPC:312 - Nodal localization of a marginal zone B-cell lymphoma (MZBCL) (nodal localization of a MALT lymphoma)
 HPC:315 : Mammary MALT lymphoma (Mammary marginal zone B-cell lymphoma)
 HPC:330 : Rectal marginal zone B-cell lymphoma (Rectal MALT lymphoma)
 JRC:15045 : Thyroid MALT lymphoma

Localization

 salivary marginal zone B-cell lymphoma (salivary MALToma)
 digestive marginal zone B-cell lymphoma
 pulmonary marginal zone B-cell lymphoma

Cytogenetics

 t(11;18)-positive MALT lymphomas

• t(11;18)(q21;q21) (60%) (14502259)

 t(11;18)-negative MALT lymphomas (11756145)

• 3q26-27 amplification
• allelic imbalances
  • 3q26-27
  • 6q23-25
  • 7q31
  • 11q23-24
  • 18q21

References

 Isaacson PG, Du MQ. MALT lymphoma: from morphology to molecules. Nat Rev Cancer. 2004 Aug;4(8):644-53. PMID: 15286744