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pigmented spindle-cell tumors of the lymph node
Friday 9 January 2015
Pigmented spindle-cell tumors of the lymph nodes; anthracosilicotic spindle-cell pseudotumor; pigmented spindle-cell tumors of the lymph node
Pigmented spindle-cell tumors of the lymph nodes have a broad differential diagnosis, including both benign and malignant neoplasms.
Synopsis
atypical polygonal cells and atypical spindle cells bland nuclear features abundant cytoplasmic anthracotic pigment
To do
immunohistochemistry
- melanoma markers
- histiocyte markers
Polarization microscopy
- minute birefringent intracellular crystals consistent with silica.
Electron microscopy
Differential diagnosis (example)
spindle-cell melanoma localization anthracosilicotic spindle-cell pseudotumor
See also
References
A case report of anthracosilicotic spindle-cell pseudotumor of mediastinal lymph node: cytologic diagnosis by endoscopic ultrasound-guided fine-needle aspiration. Varghese LR, Stanley MW, Wakely PE Jr, Lucido ML, Mallery S, Bardales RH. Diagn Cytopathol. 2005 Oct;33(4):268-72. PMID: 16138379