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replication fork

Sunday 12 June 2005

Definition: Replication fork is the region of replicating DNA in which active DNA synthesis is occurring to generate two copies of the parental DNA.

References

 Heller RC, Marians KJ. Replisome assembly and the direct restart of stalled replication forks. Nat Rev Mol Cell Biol. 2006 Dec;7(12):932-43. PMID: 17139333

 Cleary JD, Pearson CE. Replication fork dynamics and dynamic mutations: the fork-shift model of repeat instability. Trends Genet. 2005 May;21(5):272-80. PMID: 15851063