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morphogenesis

Thursday 10 July 2003

Definition: The coming into being of form. Morphogenesis involves coordinated proliferation, differentiation and spatial distribution of cells.

Types

 branching morphogenesis
 tubular morphogenesis

By organs

 renal morphogenesis in renal development
 pulmonary morphogenesis in pulmonary development
 biliohepatic morphogenesis in biliohepatic development

Anomalies

 dysmorphogenesis

See also

  organogenesis
 molecular morphogenesis

Open references

 Computational models for mechanics of morphogenesis.
Wyczalkowski MA, Chen Z, Filas BA, Varner VD, Taber LA.
Birth Defects Res C Embryo Today. 2012 Jun;96(2):132-52.
doi : 10.1002/bdrc.21013 Review.
PMID: 22692887 (free)

References

 Lecuit T, Lenne PF. Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis. Nat Rev Mol Cell Biol. 2007 Aug;8(8):633-44. PMID: 17643125

 Lecaudey V, Gilmour D. Organizing moving groups during morphogenesis. Curr Opin Cell Biol. 2006 Feb;18(1):102-7. PMID: 16352429

 Hardin J, Walston T. Models of morphogenesis: the mechanisms and mechanics of cell rearrangement. Curr Opin Genet Dev. 2004 Aug;14(4):399-406. PMID: 15261656

 Martinez-Frias ML, Frias JL, Opitz JM. Errors of morphogenesis and developmental field theory. Am J Med Genet. 1998 Apr 1;76(4):291-6. PMID: 9545092