pulmonary development
Image Gallery
[ (||image_reduire{0,60}|inserer_attribut{alt,Fetal lung 22 weeks}) ]
Definition
Developement stages
Embyonic (26 days-6 weeks): development of major airways
Pseudoglandular (6-16 weeks): development of airways to terminal bronchioles
Acinar or canalicular (16-28 weeks): development of acinus and its vascularization
Saccular (28-34 weeks): subduvision of saccules by secondary crests
Alveolar (34-39 weeks): alveolar acquisition (alveolarization)
Links
Update in Pediatric Lung Disease 2009.
References
Inanlou MR, Baguma-Nibasheka M, Kablar B. The role of fetal breathing-like movements in lung organogenesis. Histol Histopathol. 2005 Oct;20(4):1261-6. PMID: #16136506#
Warburton D, Bellusci S, De Langhe S, Del Moral PM, Fleury V, Mailleux A, Tefft D, Unbekandt M, Wang K, Shi W. Molecular mechanisms of early lung specification and branching morphogenesis. Pediatr Res. 2005 May;57(5 Pt 2):26R-37R. PMID: #15817505#
Groenman F, Unger S, Post M. The molecular basis for abnormal human lung development. Biol Neonate. 2005;87(3):164-77. PMID: #15591817#
Hislop A. Developmental biology of the pulmonary circulation. Paediatr Respir Rev. 2005 Mar;6(1):35-43. PMID: #15698814#
Shannon JM, Hyatt BA. Epithelial-mesenchymal interactions in the developing lung. Annu Rev Physiol. 2004;66:625-45. PMID: #14977416#
Chuang PT, McMahon AP. Branching morphogenesis of the lung: new molecular insights into an old problem. Trends Cell Biol. 2003 Feb;13(2):86-91. PMID: #12559759#
DiFiore JW, Wilson JM. Lung development. Semin Pediatr Surg. 1994 Nov;3(4):221-32. PMID: #7850362#