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organelle proteomics
Monday 5 July 2004
The mass-spectrometry-based identification of proteins has created opportunities for the study of organelles, transport intermediates and large subcellular structures.
Traditional cell-biology techniques are used to enrich these structures for proteomics analyses, and such analyses provide insights into the biology and functions of these structures.
See also
organelle-associated proteins
- mitochondrial proteins
- basal body proteins
- centrosomal proteins
- endoplasmic reticulum proteins
- Golgi-resident proteins
- centriolar proteins
- lysosomal proteins
- vesicle-associated proteins
- melanosome-associated proteins
- sarcomeric proteins
References
Yates JR 3rd, Gilchrist A, Howell KE, Bergeron JJ. Proteomics of organelles and large cellular structures. Nat Rev Mol Cell Biol. 2005 Sep;6(9):702-14. PMID: 16231421
Pazour GJ. Comparative genomics: prediction of the ciliary and basal body proteome. Curr Biol. 2004 Jul 27;14(14):R575-7. PMID: 15268880
Brunet S, Thibault P, Gagnon E, Kearney P, Bergeron JJ, Desjardins M. Organelle proteomics: looking at less to see more. Trends Cell Biol. 2003 Dec;13(12):629-38. PMID: 14624841