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PDCD1LG2

Monday 19 June 2017

PD-L2; B7-DC; PDL2 ; CD273

WKP

PD-L2 (or Programmed cell death 1 ligand 2) is a protein that in humans is encoded by the PDCD1LG2 gene. PDCD1LG2 has also been designated as CD273 (cluster of differentiation 273).

See also

 immune checkpois
 PD-1 and PD-L1

Links

http://ecancer.org/news/11795-tumour-pd-l2-expression-may-predict-patient-response-to-anti-pd-1-immunotherapy.php

Open references

The PD1:PD-L1/2 Pathway from Discovery to Clinical Implementation.
Bardhan K, Anagnostou T, Boussiotis VA.
Front Immunol. 2016 Dec 12;7:550. doi : 10.3389/fimmu.2016.00550. Review
PMID: 28018338 Free