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t(X;6)(p11;q23)

Friday 25 April 2008

AGCO

Tumors

 acute myeloid leukemia (AML)

Molecular biology

 transforming MYB-GATA1 fusion gene (21474671)

References

 Identification of a transforming MYB-GATA1 fusion gene in acute basophilic leukemia: a new entity in male infants. Quelen C, Lippert E, Struski S, Demur C, Soler G, Prade N, Delabesse E, Broccardo C, Dastugue N, Mahon FX, Brousset P. Blood. 2011 May 26;117(21):5719-22. PMID: 21474671

 Acute basophilic leukaemia and translocation t(X;6)(p11;q23). Dastugue N, Duchayne E, Kuhlein E, Rubie H, Demur C, Aurich J, Robert A, Sie P. Br J Haematol. 1997 Jul;98(1):170-6. PMID 97376810