Home > G. Tumoral pathology > Molecular pathology of tumors > Cancer molecular profiling > Cancer cytogenetics > hyperdiploidy
hyperdiploidy
Thursday 21 June 2007
Tumors
neuroblastomas (hyperdiploid neuroblastoma) myelomas (hyperdiploid myeloma) acute lymphoblastic leukemia (ALL) (17431878)
- Children with acute lymphoblastic leukemia (ALL) and high hyperdiploidy (>50 chromosomes) are considered to have a relatively good prognosis.
- Specific extra chromosomes are not random. (17431878)
See also
hyperdiploid tumors
References
Heerema NA, Raimondi SC, Anderson JR, Biegel J, Camitta BM, Cooley LD, Gaynon PS, Hirsch B, Magenis RE, McGavran L, Patil S, Pettenati MJ, Pullen J, Rao K, Roulston D, Schneider NR, Shuster JJ, Sanger W, Sutcliffe MJ, van Tuinen P, Watson MS, Carroll AJ. Specific extra chromosomes occur in a modal number dependent pattern in pediatric acute lymphoblastic leukemia. Genes Chromosomes Cancer. 2007 Jul;46(7):684-93. PMID: 17431878
Chng WJ, Ketterling RP, Fonseca R. Analysis of genetic abnormalities provides insights into genetic evolution of hyperdiploid myeloma. Genes Chromosomes Cancer. 2006 Dec;45(12):1111-20. PMID: 16955468