Prostate

• paraganglion in prostate
  30 August 2012

  Paraganglion in Prostate Biopsies
  Paraganglia are usually located external to the prostate near postero-lateral neurovascular bundles. Occasionally, they may be sampled in prostate needle biopsies.
  Paraganglia are composed of cells with clear or amphophilic cytoplasm, inconspicuous nucleoli, and a prominent vascular pattern. They are present within smooth muscle bundles away from benign acini. When present in prostate needle biopsies, paraganglia must be distinguished from high-grade (...)

• neuroganglionar cells in prostate
  30 August 2012

  Ganglia in Prostate Biopsies
  Ganglia are usually found in the fibromuscular tissue external to the prostate; sometimes, they may be found within the outer regions of prostate itself.
  In needle biopsies, they are usually located at one of the ends of the core.
  Ganglia found in prostate needle biopsies should not be mistaken for high-grade carcinoma. The intracellular pigment and satellite cells around neurons have to be noted.
  Link
  WebPathology 1 : Ganglia in Prostate Biopsies (...)

• skeletal muscle in prostate
  30 August 2012

  Skeletal Muscle in Prostate Biopsies
  Skeletal muscle fibers of the urogenital diaphragm extend into the apical and anterior peripheral regions of the prostate. Not infrequently, skeletal muscle fibers are seen in needle biopsies from those regions.
  Link
  Webpathology: Skeletal Muscle in Prostate Biopsies

• spermatozoa in prostate
  30 August 2012

  spermatozoa in prostate biopsy
  Spermatozoa are seen in approximately 1% of prostate needle biopsies (unpublished personal observation).
  Link
  WebPathology : spermatozoa in prostate biopsy

• crystalloids in prostate
  30 August 2012

  Eosinophilic crystalloids
  Eosinophilic crystalloids are not specific for cancer.
  They can be present within the lumen of a large benign gland.
  They can also be seen in atypical adenomatous hyperplasia (AAH), PIN, and other conditions.
  Etiology
  crystalloids in benign glands
  crystalloids in prostatic adenocarcinoma
  Link
  WebPathology: Crystalloids in Benign Glands

• neuroendocrine cells in atrophic prostate glands
  30 August 2012

  Neuroendocrine cells are seen in benign prostate, high-grade PIN, and cancer.
  They are most abundant near verumontanum.
  Many neuroendocrine cells with large eosinophilic granules (Paneth cell-like change) can be seen in atrophic prostate glands.
  Links
  WebPathology

• prostatic basal cells
  30 August 2012

  prostatic basal cell layer; prostate basal cell
  Basal cells are present in a continuous layer in most benign glands.
  The antibodies to high molecular weight cytokeratin 34bE12 stain basal cells but not secretory or stromal cells in the prostate.
  Besides cancer, the basal cell layer may be disrupted in atrophy, inflammation, atypical adenomatous hyperplasia (adenosis), and high-grade PIN.
  Links (...)

• prostate corpora amylacea
  30 August 2012

  Corpora amylacea are inspissated secretions that may have a lamellated appearance.
  Usually Corpora amylacea are pink or purple in appearance. Sometimes they may be golden-brown.
  Link
  WebPathology 1
  WebPathology 2

• prostatic glands
  30 August 2012

  Benign glands
  In a benign gland, the luminal contour shows tufts and papillary infoldings. The tall secretory epithelial cells have pale clear cytoplasm and uniform round or oval nuclei. Prominent nucleoli are not seen. Many basal cells can be identified.
  Luminal contents
  3 prostatic gland luminal contents associated with cancer https://twitter.com/GladellPaner/status/1442820123165872130
  Links (...)

• prostatic atypical basal cell hyperplasia
  30 August 2012

  prostate atypical basal cell hyperplasia
  Atypical adenomatous hyperplasia (adenosis) - when seen in a needle biopsy - is one of the most challenging benign mimics of cancer.
  Synopsis
  In rare instances, basal cell hyperplasia shows prominent nucleoli. This is referred to as atypical basal cell hyperplasia. In most cases, this is in response to inflammation nearby.
  The immunostain for high molecular weight cytokeratin 34bE12 nicely demonstrates the fragmented basal cell layer in this (...)

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