Blood and immunity

• Waldenstrom macroglobulinemia
  6 January 2004

  Waldenstrom disease; Waldenstrom’s macroglobulinemia
  Digital case
  JRC:7796 : Waldenstrom’s macroglobulinemia.
  Definition: Waldenstrom macroglobulinemia (WM) is a clinicopathologic syndrome in which a B-cell neoplasm involving the bone marrow, usually lymphoplasmacytic lymphoma (LPL), is associated with immunoglobulin M paraprotein in the serum.
  See also: lymphoplasmacytic lymphoma (LPL)
  Etiology
  lymphoplasmacytic lymphoma
  lymphoplasmacytoid lymphoma
  small lymphocytic (...)

• Kimura disease
  29 December 2003

  Kimura’s disease

• angiolymphoid hyperplasia with eosinophilia
  29 December 2003

  Angiolymphoid hyperplasia with eosinophilia (ALHE) is commonly regarded an angioproliferative process characterized by the presence of prominent, bizarrely shaped blood vessels. These vessels are accompanied by an eosinophilic inflammatory infiltrate that is thought to be a reactive component. HALE
  Images
  Angiolymphoid hyperplasia with eosinophilia with lymphoid https://twitter.com/ARP_Press/status/846860599590039552 https://twitter.com/TheKarenPinto/status/954328802859024384 (...)

• fibrin-ring granuloma
  29 December 2003

  fibrin ring granuloma, doughnut granuloma
  Definition: Fibrin ring or "doughnut" granulomas are small, non-necrotizing granulomas with a very distinctive appearance that are usually found in the liver and bone marrow in patients with Q fever. These granulomas characteristically contain a ring-like structure consisting of fibrinoid material; they may or may not have a centrally located fat vacuole(s).
  Localization
  hepatic fibrin-ring granuloma
  medullary fibrin-ring granuloma
  Etiology (...)

• emperipolesis
  16 December 2003

  Digital cases
  HPC:290 : Emperipolesis in Rosai-Dorfman disease
  Images
  https://twitter.com/dozing_dog/status/724843235567345664
  https://twitter.com/BeynonMD/status/733528203260661760
  https://twitter.com/BeynonMD/status/733528203260661760
  https://twitter.com/DrBMcGinn/status/1496200793862594571
  Synopsis
  numerous CD68-positive/S-100-negative histiocytes containing viable neoplastic hematopoietic cells in their cytoplasm
  Etiology
  Rosai-Dorfman disease
  Langerhans cell (...)

• Rosai-Dorfman disease
  16 December 2003

  sinus histiocytosis with massive lymphadenopathy

• immunoglobulin heavy chain deposition disease
  12 December 2003
• plasma cell dyscrasia
  12 December 2003

  Notes
  https://twitter.com/pathodoodles/status/1346450979135356935
  See also
  plasma cell
  dyscrasia

• monoclonal immunoglobulin deposition disease
  12 December 2003

  Classification
  immunoglobulin light chain deposition disease
  immunoglobulin heavy chain deposition disease

• T/NK lymphomas
  8 December 2003

  Digital case
  HPC:316 : EBV-associated nasal T/NK lymphoma
  Types
  EBV-associated nasal T/NK lymphomas
  See also
  T/NK leukemias

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