Stomach

• parietal cell hyperplasia
  10 September 2014

  The oxyntic mucosa show marked hyperplasia and hypertrophy of the parietal cells. Some of these cells can be vacuolated, and many can display protrusions of apical cytoplasm into dilated oxyntic glands filled with inspissated eosinophilic material.
  Etiology
  chronic omeprazole therapy (#8888719#)
  long-term antiacids administration
  Association achlorhydria, parietal cell hyperplasia, and multiple gastric carcinoids (#15958864#)
  atrophic mucosa of autoimmune (...)

• adenomatoid hyperplasia of enterochromaffin-like cells
  27 December 2013

  Definition: Defined as compact collections of 5 or more ECL micronodules, lying close to each other, in the deep lamina propria. No more than 150 microns in maximum size.
  See also
  hyperplasia of enterochromaffin-like cells diffuse hyperplasia of enterochromaffin-like cells linear hyperplasia of enterochromaffin-like cells micronodular hyperplasia of enterochromaffin-like cells adenomatoid hyperplasia of enterochromaffin-like cells
  Reference
  Hyperplastic, dysplastic, and neoplastic (...)

• micronodular hyperplasia of enterochromaffin-like cells
  27 December 2013

  micronodular hyperplasia
  Synopsis
  micronodular clusters of at least 5 cells not exceeding the diameter of gastric glands, lying within the gastric glands, or within the lamina propria at the deep aspect of the oxyntic glands.
  These collections do not exceed 150 microns in maximum size.
  See also
  hyperplasia of enterochromaffin-like cells diffuse hyperplasia of enterochromaffin-like cells linear hyperplasia of enterochromaffin-like cells micronodular hyperplasia of (...)

• linear hyperplasia of enterochromaffin-like cells
  27 December 2013

  ECL linear hyperpalsia
  Synopsis
  linear hyperplasia is characterized by a chain of at least 5 ECL cells, growing in a sleeve-like manner within the gastric glands.
  See also
  hyperplasia of enterochromaffin-like cells diffuse hyperplasia of enterochromaffin-like cells linear hyperplasia of enterochromaffin-like cells micronodular hyperplasia of enterochromaffin-like cells adenomatoid hyperplasia of enterochromaffin-like cells
  Reference
  Hyperplastic, dysplastic, and neoplastic (...)

• diffuse hyperplasia of enterochromaffin-like cells
  27 December 2013

  simple hyperplasia of enterochromaffin-like cells
  Definition: Diffuse or simple hyperplasia of gastric ECL is characterized by an increase (>2 fold) in ECL number.
  See also
  hyperplasia of enterochromaffin-like cells diffuse hyperplasia of enterochromaffin-like cells linear hyperplasia of enterochromaffin-like cells micronodular hyperplasia of enterochromaffin-like cells adenomatoid hyperplasia of enterochromaffin-like cells
  Reference
  Hyperplastic, dysplastic, and neoplastic (...)

• enterochromaffin-like cell
  27 December 2013

  enterochromaffin-like (ECL) cells; ECL cells WP
  Endocrine cells of the gastric oxyntic mucosa, and especially the enterochromaffin-like (ECL) cells, are the progenitors of gastrin-promoted proliferative lesions whose tumorigenic potential largely depends on the background condition in which they arise.
  ECL cells are the main neuroendocrine cells of the stomach, comprising approximately 70% of the gastric NE cells, and represent the major histamine source of the gastric mucosa.
  ECL (...)

• gastric endocrine cells
  27 December 2013

  Endocrine cells of the gastric oxyntic mucosa, and especially the enterochromaffin-like (ECL) cells, are the progenitors of gastrin-promoted proliferative lesions whose tumorigenic potential largely depends on the background condition in which they arise.
  Pathology
  The endocrine cell lesions have been classified as:
  pseudohyperplasia (cell clustering unassociated with cell proliferation)
  hyperplasia (diffuse, linear, micronodular, adenomatoid)
  dysplasia (enlarged, adenomatous or (...)

• gastric neuroendocrine carcinoma
  15 July 2013

  neuroendocrine carcinoma of the stomach
  Neuroendocrine carcinoma (NEC) of the stomach has been recognized as a highly malignant tumor.
  Reference
  Neuroendocrine carcinoma of the stomach: morphologic and immunohistochemical characteristics and prognosis. Ishida M, Sekine S, Fukagawa T, Ohashi M, Morita S, Taniguchi H, Katai H, Tsuda H, Kushima R. Am J Surg Pathol. 2013 Jul;37(7):949-59. doi:10.1097/PAS.0b013e31828ff59d . PMID: (...)

• doxycycline-induced gastric lesions
  12 July 2013

  Doxycycline-induced Gastric With Vascular Degeneration.
  References
  Doxycycline-induced Gastric and Esophageal Mucosal Injuries With Vascular Degeneration. Xiao SY, Zhao L, Hart J, Semrad CE. Am J Surg Pathol. 2013 Jul;37(7):1115-6. doi:10.1097/PAS.0b013e31828f5b3a . PMID: #23759935#

• foveolar cell
  1 May 2013

  foveolar cells
  Definition: Foveolar cells are mucus producing cells which cover the inside of the stomach, protecting it from the corrosive nature of gastric acid.
  Foveolar cells are also known as "surface mucous cells" or "mucous neck cells", depending on the location. These cells line the gastric mucosa and gastric pits.
  The mucous secreting cells of the stomach can be distinguished histologically from the intestinal goblet cells.
  See also
  goblet (...)

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