Pancreas

• pancreatic anomalies
  9 January 2017

  By components
  anomalies of exocrine pancreas pancreatic ductal anomalies pancreatic acinar anomalies
  anomalies of endocrine pancreas diabetes mellitus
  Pancreatic anomalies - Examples
  congenital pancreatic anomalies agenesis annular pancreas heterotopic pancreas / pancreatic hetrotopia nesidioblastosis pancreas divisum
  pancreatic inflammation ! pancreatitis pancreatic acute inflammation pancreatic chronic inflammation pancreatic eosinophilic inflammation
  pancreatic cysts / (...)

• pancreatic pathology
  9 January 2017

  PO
  Definition: Pancreatic pathology is the study of pancreatic diseases and pancreatic anomalies.
  Chapters
  pancreatic anomalies
  pancreatic diseases
  pancreatic tumors
  Pancreatic anomalies - Examples
  congenital pancreatic anomalies agenesis annular pancreas heterotopic pancreas / pancreatic hetrotopia nesidioblastosis pancreas divisum
  pancreatic inflammation ! pancreatitis pancreatic acute inflammation pancreatic chronic inflammation pancreatic eosinophilic inflammation (...)

• pancreatic diseases
  9 January 2017

  Types
  pancreatic malformative diseases
  pancreatic genetic diseases
  pancreatic infectious diseases
  pancreatic dysimmune diseases
  pancreatic metabolic diseases
  pancreatic tumoral diseases / pancreatic tumors
  See also
  pancreatic anomalies
  pancreatic pathology
  pancreatic tumors
  diseases

• pancreatic anomalies
  9 January 2017

  See also
  pancreatic diseases
  morphological anomalies

• PancraGEN
  14 November 2016

  PancraGEN by Interpace Diagnostics
  Links
  PancraGEN by Interpace Diagnostics http://www.interpacediagnostics.com/pancragen/

• acinar-to-ductal metaplasia
  19 October 2016

  acinar-to-ductal metaplasia lesion in pancreas; pancreatic acinar-to-ductal metaplasia
  Molecular biology
  shortened telomeres are found in PanIN-associated acinar-to-ductal metaplasias, but not in isolated acinar-to-ductal metaplasia lesions. These results indicate that isolated acinar-to-ductal metaplasias are not a precursor to PanIN. They support the hypothesis that PanIN-associated acinar-to-ductal metaplasias arise secondary to PanIN lesions.
  See also
  PanIns / PanIn
  Open (...)

• KRAS-associated pancreatic tumors
  19 October 2016

  Open references
  KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin.
  Shi C, Hong SM, Lim P, Kamiyama H, Khan M, Anders RA, Goggins M, Hruban RH, Eshleman JR. Mol Cancer Res. 2009 Feb;7(2):230-6.
  doi:10.1158/1541-7786.MCR-08-0206.
  PMID: #19208745# Free
  Paywall references
  Sensitive and quantitative detection of KRAS2 gene mutations in pancreatic duct juice differentiates (...)

• pancreatic cystic neuroendocrine tumors
  19 October 2016

  Cystic pancreatic neuroendocrine tumor
  See also
  pancreatic neuroendocrine tumors
  References
  Cystic pancreatic neuroendocrine tumors: a clinicopathologic study.
  Singhi AD, Chu LC, Tatsas AD, Shi C, Ellison TA, Fishman EK, Kawamoto S, Schulick RD, Wolfgang CL, Hruban RH, Edil BH.
  Am J Surg Pathol. 2012 Nov;36(11):1666-73.
  doi:10.1097/PAS.0b013e31826a0048.
  PMID: (...)

• pancreatic well-differentiated neuroendocrine tumor
  19 October 2016

  well-differentiated pancreatic neuroendocrine tumors
  Open references
  Grading of well-differentiated pancreatic neuroendocrine tumors is improved by the inclusion of both Ki67 proliferative index and mitotic rate. McCall CM, Shi C, Cornish TC, Klimstra DS, Tang LH, Basturk O, Mun LJ, Ellison TA, Wolfgang CL, Choti MA, Schulick RD, Edil BH, Hruban RH.
  Am J Surg Pathol. 2013 Nov;37(11):1671-7.
  doi:10.1097/PAS.0000000000000089.
  PMID: #24121170# (...)

• pancreatic neuroendocrine carcinoma
  19 October 2016

  neuroendocrine carcinomas of the pancreas
  Open references
  Small cell and large cell neuroendocrine carcinomas of the pancreas are genetically similar and distinct from well-differentiated pancreatic neuroendocrine tumors.
  Yachida S, Vakiani E, White CM, Zhong Y, Saunders T, Morgan R, de Wilde RF, Maitra A, Hicks J, Demarzo AM, Shi C, Sharma R, Laheru D, Edil BH, Wolfgang CL, Schulick RD, Hruban RH, Tang LH, Klimstra DS, Iacobuzio-Donahue CA.
  Am J Surg Pathol. 2012 Feb;36(2):173-84. (...)

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