single-cell analyses in cancer
Single-cell approaches are used to study EMT-related markers of CTCs for metastatic prostate cancer detection and prediction. Markers are identified using microfluidics and atomic force microscope (AFM) for molecular profiling and nanomechanical and nanochemical phenotypes of CTCs, respectively.
Reference
Direct, genome-wide assessment of DNA mutations in single cells. Gundry M, Li W, Maqbool SB, Vijg J. Nucleic Acids Res. 2012 Mar;40(5):2032-40. (...)
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Biopathology 2014
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single-cell analysis in cancer
4 January 2014