Microscopy

Articles

• chronic inflammation
  1 June 2004

  Definition: Inflammation in which mononuclear leukocytes, including lymphocytes, plasma cells (plasmocytes), and macrophages (histiocytes) predominate.
  Occasional small lymphoid aggregates without germinal centers are to be expected, but presence of germinal centers is prima facie evidence of chronic inflammation.
  Prominent numbers of eosinophils and mast cells, and fibrocytes with fibrosis when there is tissue repair, are often included in the overall picture of chronic inflammation. (...)

• renal hypoplasias
  19 February 2004

  hypoplastic kidneys, renal hypoplasia

• Schiller-Duvall body
  14 October 2003

  Schiller-Duvall bodies
  Definition: Schiller-Duvall body is a morphological pattern seen in endodermal sinus tumor (yolk sac tumor). It consists in a central vessel surrounded by tumor cells in a cystic space often lined by flattened tumor cells.
  Schiller-Duvall body is a structure seen in the endodermal sinus pattern of yolk sac tumor. The whole structure being contains in a cystic space often lined by flattened tumor cells.
  Images
  Retroperitoneal mass - AFP, AE1AE3 and glypican (...)

• spindle cell hemangioma
  14 June 2004

  fusiform cell hemangioendothelioma, spindle cell hemangioendothelioma
  Definition: Spindle cell haemangioendothelioma is an entirely benign, non-recurring lesion which has been renamed "spindle cell hemangioma".
  Images
  Spindle cell hemangioma
  https://twitter.com/histiocytosisX/status/715931392580927488
  https://twitter.com/rlhutton/status/864217351474081792
  Similarly, it is now appreciated that as many as 20–30% of epithelioid haemangioendotheliomas may give rise to distant metastases (...)

• starry sky appearance
  1 December 2005

  starry-sky appearance
  Synopsis
  cellular debris-laden macrophages
  Images
  Burkitt lymphoma. Starry sky (lots of apoptosis = no anti-apoptosis protein = BCL2 neg), 100% Ki-67 https://twitter.com/KyleBradleyMD/status/733661552948187136
  mammary carcinomas https://twitter.com/went2Harvard1nc/status/733027224022982656
  Exemples
  Burkitt lymphoma
  lymphoblastic lymphoma
  mammary carcinomas https://twitter.com/went2Harvard1nc/status/733027224022982656
  Images
  perineural invasion (...)

• abscess
  9 June 2004

  abcesses
  Definition: Abscesses are localized collections of purulent inflammatory tissue caused by suppuration buried in a tissue, an organ, or a confined space. They are produced by deep seeding of pyogenic bacteria into a tissue.
  Abscesses have a central region that appears as a mass of necrotic leukocytes and tissue cells. There is usually a zone of preserved neutrophils around this necrotic focus, and outside this region vascular dilation and parenchymal and fibroblastic proliferation (...)

• Echinococcus granulosus
  7 December 2005

  Definition: Echinococcus granulosus, also called the Hydatid worm, is a cyclophyllid cestode that parasitizes the small intestine of canids as an adult, but which has important intermediate hosts such as livestock and humans, where it causes hydatid disease.
  Images
  hepatic cystic echinococcosis / Echinococcus granulosus
  https://twitter.com/RhondaYantiss/status/851519941299851265
  The adult tapeworm is about 5 mm long and has three proglottids ("segments") when intact. Like all (...)

• bone marrow metastasis
  24 February 2005

  References
  Roodman GD. Mechanisms of bone metastasis. N Engl J Med. 2004 Apr 15;350(16):1655-64. PMID: #15084698#

• lymphomatoid granulomatosis
  12 August 2004

  angiocentric immunoproliferative lesion, AIL, angiocentric lymphoproliferative lesion, benign lymphocytic angiitis and granulomatosis
  Digital cases
  JRC:1608 : Pulmonary lymphomatoid granulomatosis.
  JRC:19434 : Pulmonary lymphomatoid granulomatosis.
  Definition: Lymphomatoid granulomatosis is a rare lesional syndrome associated with Epstein-Barr virus EBV-associated B-cell LPD or peripheral T-cell lymphoma.
  Lymphomatoid granulomatosis is an angio-destructive lymphoproliferative (...)

• colorectal adenoma
  12 May 2004

  colorectal adenomas ; TA/TVA
  Definition: Adenomas, the benign glandular neoplasms that precede colon cancer development, originate from the intestinal epithelium. They occur singly or multiply. When multiple, the patients may have a genetic predisposition syndrome for colorectal cancer.
  See also : colorectal adenoma with adenocarcinoma
  Endoscopy
  Small (< 5 mm) colorectal polyps commonly affect individuals older than 50 years of age and adenomas account for 60% to 66% ofthese small (...)

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