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chorangiomatosis

Thursday 2 February 2006

Diffuse chorangiomatosis (CM) is characterized by multifocal stem villi enlargement containing increased number of small vessels with alpha-smooth muscle actin positive cells in the walls in a dense reticulin fibers-rich stroma.

Predisposition

 Beckwith-Wiedemann syndrome (1570237)

References

 Saltzman M, Drut M, Drut R. Luteinized cystic ovarian hyperplasia associated with placentomegaly due to chorangiomatosis. Fetal Pediatr Pathol. 2005 Jan-Feb;24(1):31-7. PMID: 16175750

 Drut R, Drut RM, Toulouse JC. Hepatic hemangioendotheliomas, placental chorioangiomas, and dysmorphic kidneys in Beckwith-Wiedemann syndrome. Pediatr Pathol. 1992 Mar-Apr;12(2):197-203. PMID: 1570237