Ebola
Ebola virus (EBOV) causes severe haemorrhagic fever leading to up to 90% lethality. Two major factors in EBOV pathogenesis are the impairment of the immune response and vascular dysfunction.
References
Hoenen T, Groseth A, Falzarano D, Feldmann H. Ebola virus: unravelling pathogenesis to combat a deadly disease. Trends Mol Med. 2006 May;12(5):206-15. PMID: #16616875#
Hensley LE, Jones SM, Feldmann H, Jahrling PB, Geisbert TW. Ebola and Marburg viruses: pathogenesis and development of countermeasures. Curr Mol Med. 2005 Dec;5(8):761-72. PMID: #16375711#