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MLH1-associated pediatric cancer syndrome
Monday 14 February 2011
See also
MMR-associated pediatric cancer syndrome MMR genes MMR deficiency hereditary nonpolyposis colorectal cancer (HNPCCs)
References
Homozygosity at variant MLH1 can lead to secondary mutation in NF1, neurofibromatosis type I and early onset leukemia. Alotaibi H, Ricciardone MD, Ozturk M. Mutat Res. 2008 Jan 1;637(1-2):209-14. PMID: 17889038
Gastrointestinal cancers and neurofibromatosis type 1 features in children with a germline homozygous MLH1 mutation. Gallinger S, Aronson M, Shayan K, Ratcliffe EM, Gerstle JT, Parkin PC, Rothenmund H, Croitoru M, Baumann E, Durie PR, Weksberg R, Pollett A, Riddell RH, Ngan BY, Cutz E, Lagarde AE, Chan HS. Gastroenterology. 2004 Feb;126(2):576-85. PMID: 14762794