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Neutropenia

Etiology

- hereditary neutropenia

  • infantile genetic agranulocytosis (Kostmann syndrome)
  • chronic congenital neutropenia
    • cyclic neutropenia
    • benign chronic neutropenia
    • severe congenital neutropenia
  • reticular dysgenesis
  • myelokathexis
  • cartilage-hair hypoplasia
  • dyskeratosis congenita
  • Chediak-Higashi syndrome

- acquired neutropenia

  • transient acquired neutropenia
    • infections (viaral, bacterial, tularemia)
    • burns
    • drugs
    • hemodialysis
    • vitanin B12 deficiency
    • folate deficiency
  • chronic acquired neutropenia
    • myelophthisic process
    • hematologic malignancies (Leukemias, Lymphomas)
    • myelodysplasia
    • autoimmunity
    • hypersplenism
    • idiopathic acquired neutropenia