single-cell LOH detection
References
Lespinet V, Terraz F, Recher C, Campo E, Hall J, Delsol G, Al Saati T. Single-cell analysis of loss of heterozygosity at the ATM gene locus in Hodgkin and Reed-Sternberg cells of Hodgkin’s lymphoma: ATM loss of heterozygosity is a rare event. Int J Cancer. 2005 May 10;114(6):909-16. PMID: #15645496#
Klein CA, Schmidt-Kittler O, Schardt JA, Pantel K, Speicher MR, Riethmuller G. Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cells. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4494-9. PMID: #10200290#