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Kasabach-Merritt syndrome

Definition: Kasabach-Merritt phenomenon (KMP) is characterized by profound thrombocytopenia, microangiopathic hemolytic anemia, a consumptive coagulopathy, and an enlarging vascular lesion.

Kasabach-Merritt phenomenon is a serious coagulopathy associated with kaposiform hemangioendothelioma (KHE), tufted angioma, and possibly other vascular neoplasms.

Classification

- vascular tumors

  • kaposiform hemangioendothelioma
  • tufted angioma
  • multifocal lymphangioendotheliomatosis with thrombocytopenia (#15148106#)
  • angiosarcoma (#12410374#, #17505172#)
  • angioblastoma (#9764180#)

- vascular dysplasias

  • diffuse splenic hemangiomatosis (#10564388#)
  • complex vascular malformations (#12220282#)

- fibrosarcoma (#14726860#)