GNA11

Guanine nucleotide-binding protein subunit alpha-11 is a protein that in humans is encoded by the GNA11 gene. Together with GNAQ (its paralogue), it functions as a Gq alpha subunit.

Pathology

 GNA11 Mutation in Cutaneous Origin Melanoma (26825879)

 Mosaic Activating Mutations in GNA11 and GNAQ Are Associated with Phakomatosis Pigmentovascularis and Extensive Dermal Melanocytosis. (26778290)

 High frequency of GNA14 , GNAQ , and GNA11 mutations in cherry hemangioma: a histopathological and molecular study of 85 cases indicating GNA14 as the most commonly mutated gene in vascular neoplasms. 2019
https://www.nature.com/articles/s41379-019-0284-y

Open references

 High frequency of GNA14, GNAQ, and GNA11 mutations in cherry hemangioma: a histopathological and molecular study of 85 cases indicating GNA14 as the most commonly mutated gene in vascular neoplasms. 2019
https://www.nature.com/articles/s41379-019-0284-y

 GNA11 Mutation in a Patient With Cutaneous Origin Melanoma: A Case Report.
Patel SP, Kim DW, Lacey CL, Hwu P.
Medicine (Baltimore). 2016 Jan;95(4):e2336. doi : 10.1097/MD.0000000000002336
PMID: 26825879

 Mosaic Activating Mutations in GNA11 and GNAQ Are Associated with Phakomatosis Pigmentovascularis and Extensive Dermal Melanocytosis.
Thomas AC, Zeng Z, Rivière JB, O’Shaughnessy R, Al-Olabi L, St-Onge J, Atherton DJ, Aubert H, Bagazgoitia L, Barbarot S, Bourrat E, Chiaverini C, Chong WK, Duffourd Y, Glover M, Groesser L, Hadj-Rabia S, Hamm H, Happle R, Mushtaq I, Lacour JP, Waelchli R, Wobser M, Vabres P, Patton EE, Kinsler VA.
J Invest Dermatol. 2016 Apr;136(4):770-8. doi : 10.1016/j.jid.2015.11.027
PMID: 26778290