Home > A. Molecular pathology > Fusion genes > IGF3BP3-THADA
IGF3BP3-THADA
Friday 17 February 2017
Pathology
THADA fusion is a mechanism of IGF2BP3 activation and IGF1R signaling in thyroid cancer. ( 28193878 )
most IGF3BP3-THADA positive thyroid neoplasms are well circumscribed and have subtle nuclear alterations.
- https://twitter.com/chioseasi/status/831325327729258497
- https://twitter.com/chioseasi/status/831324383645986821
- https://twitter.com/chioseasi/status/831324780615888896
References
THADA fusion is a mechanism of IGF2BP3 activation and IGF1R signaling in thyroid cancer. Panebianco F, Kelly LM, Liu P, Zhong S, Dacic S, Wang X, Singhi AD, Dhir R, Chiosea SI, Kuan SF, Bhargava R, Dabbs D, Trivedi S, Gandhi M, Diaz R, Wald AI, Carty SE, Ferris RL, Lee AV, Nikiforova MN, Nikiforov YE. Proc Natl Acad Sci U S A. 2017 Feb 13. pii: 201614265. doi : 10.1073/pnas.1614265114 PMID: 28193878