Home > D. Systemic pathology > Hematopathology > Spleen > spleen in AIDS
spleen in AIDS
Saturday 18 May 2013, by
Prior to highly active antiretroviral therapy (HAART), typical findings were:
white pulp depletion red pulp hemosiderin deposition splenic spindle cell proliferation splenic perivascular hyalinization also infectious and malignant infiltrates (Mod Pathol 2002;15:406)
Post-highly active antiretroviral therapy (HAART) findings include less frequent white pulp depletion, but similar rates of splenic involvement by atypical mycobacteria and CMV in those with systemic disease.