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ROS1
Friday 15 March 2013
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Pathology
ROS1 rearrangement in lung adenocarcinoma
- ROS1-rearranged pulmonary adenocarcinoma
ROS1 rearrangement in gastric adenocarcinoma.(23400546)
- ROS1-rearranged lung adenocarcinoma
PDGFRB-ROS1 gene fusion between ROS1 and PDGFRB in :
- ALK-negative inflammatory myofibroblastic tumor
Targeted therapy
Open references
Molecular characterization of inflammatory myofibroblastic tumors with frequent ALK and ROS1 gene fusions and rare novel RET rearrangement.
Antonescu CR, Suurmeijer AJ, Zhang L, Sung YS, Jungbluth AA, Travis WD, Al-Ahmadie H, Fletcher CD, Alaggio R. Am J Surg Pathol. 2015 Jul;39(7):957-67. doi : 10.1097/PAS.0000000000000404
PMID: 25723109 Free
Paywall References
ROS1-Rearranged Lung Cancer: A Clinicopathologic and Molecular Study of 15 Surgical Cases. Yoshida A, Kohno T, Tsuta K, Wakai S, Arai Y, Shimada Y, Asamura H, Furuta K, Shibata T, Tsuda H. Am J Surg Pathol. 2013 Apr;37(4):554-62. doi : 10.1097/PAS.0b013e3182758fe6 PMID: 23426121
Identification of ROS1 rearrangement in gastric adenocarcinoma. Lee J, Lee SE, Kang SY, Do IG, Lee S, Ha SY, Cho J, Kang WK, Jang J, Ou SH, Kim KM. Cancer. 2013 May 1;119(9):1627-35. doi : 10.1002/cncr.27967 PMID: 23400546