coccidioidomycosis

Definition: Coccidioidomycosis is a deep mycosis rare in Europe. Coccidioidomycosis should be considered in any patient who presents with meningitis suggestive of tuberculosis who has traveled to endemic zones. Cutaneous dissemination secondary to a ventricular cardiac shunt is rare.

Digital case

 JRC:5152 : Coccidioidomycosis in lactating breast.

Images

  coccidioidomycosis : Coccidioides immitis

• https://twitter.com/azdermpath/status/703682608899592192
• https://twitter.com/JonLaiMD/status/1494096850781151238

 Lymphadenitis Infectious: Coccidioides immitis / San Joaquin Valley Fever

• https://twitter.com/AiMMe77/status/755158590583746560

 Coccidioidomycotic arthrospores in skin biopsy

• https://twitter.com/AnnieMorrisonMD/status/797852178597773312

 74yo male ear R/O BCC factitial infection

• https://twitter.com/azdermpath/status/764127245141061632

Localization

 pulmonary coccidioidomycosis
 cutaneous coccidioidomycosis
 menigeal coccidioidomycosis
 mammary coccidioidomycosis
 nodal coccidioidomycosis

Diagnosis

 In situ hybridization for Coccidioides immitis 5.8S ribosomal RNA sequences in FFPE (20502187)

See also

 Coccidies sp.

• Coccidioides immitis

 invasive fungal diseases

• paracoccidioidomycosis

References

 In situ hybridization for Coccidioides immitis 5.8S ribosomal RNA sequences in formalin-fixed, paraffin-embedded pulmonary specimens using a locked nucleic acid probe: a rapid means for identification in tissue sections. Montone KT, Litzky LA, Feldman MD, Peterman H, Mathis B, Baliff J, Kaiser LR, Kucharczuk J, Nachamkin I. Diagn Mol Pathol. 2010 Jun;19(2):99-104. PMID: 20502187

 Coccidioidomycosis in a lung transplant recipient acquired from the donor graft in France. Brugière O, Forget E, Biondi G, Métivier AC, Mal H, Dauriat G, Faussart A, Dupont B, Lortholary O, Dromer F. Transplantation. 2009 Dec 15;88(11):1319-20. PMID: 19996932