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4p12 amplification

Wednesday 21 April 2010

Target genes - driver genes

 PDGFRA

Tumors (Examples)

 non-small cell lung cancer (19755855)

References

 Amplification of chromosomal segment 4q12 in non-small cell lung cancer. Ramos AH, Dutt A, Mermel C, Perner S, Cho J, Lafargue CJ, Johnson LA, Stiedl AC, Tanaka KE, Bass AJ, Barretina J, Weir BA, Beroukhim R, Thomas RK, Minna JD, Chirieac LR, Lindeman NI, Giordano T, Beer DG, Wagner P, Wistuba II, Rubin MA, Meyerson M. Cancer Biol Ther. 2009 Nov;8(21):2042-50. PMID: 19755855