thymic mucinous adenocarcinoma
Synopsis
islands and strips of tumor cells floating in large pools of extracellular mucin
numerous psammoma bodies
dilated glands, cords
small nests infiltrating the thymic cyst wall
mucin production
Immunohistochemistry
positive for cytokeratin (CK) 7
negative for CD5
Associations
thymic cyst with areas of transition from benign to dysplastic epithelium
Differential diagnosis
malignant mediastinal tumors
References
Ra SH, Fishbein MC, Baruch-Oren T, Shintaku P, Apple SK, Cameron RB, Lai CK. Mucinous adenocarcinomas of the thymus: report of 2 cases and review of the literature. Am J Surg Pathol. 2007 Sep;31(9):1330-6. PMID: #17721187#