Acanthamoeba sp.
Acanthamoeba species are known to cause 2 well-described entities: (1) granulomatous amoebic encephalitis (GAE), which usually affects immunocompromised hosts, and (2) keratitis, which typically follows trauma associated with contamination of water or contact lenses. Less common manifestations include pneumonitis and a subacute granulomatous dermatitis.
Synopsis
granulomatous amoebic encephalitis (GAE) in immunocompromised hosts
keratitis, typically follows trauma associated with contamination of water or contact lenses
pneumonitis
subacute granulomatous dermatitis
References
Walia R, Montoya JG, Visvesvera GS, Booton GC, Doyle RL. A case of successful treatment of cutaneous Acanthamoeba infection in a lung transplant recipient. Transpl Infect Dis. 2007 Mar;9(1):51-4. PMID: #17313473#
MacLean RC, Hafez N, Tripathi S, Childress CG, Ghatak NR, Marciano-Cabral F. Identification of Acanthamoeba sp. in paraffin-embedded CNS tissue from an HIV+ individual by PCR. Diagn Microbiol Infect Dis. 2007 Mar;57(3):289-94. PMID: #17254732#
Sissons J, Alsam S, Goldsworthy G, Lightfoot M, Jarroll EL, Khan NA. Identification and properties of proteases from an Acanthamoeba isolate capable of producing granulomatous encephalitis. BMC Microbiol. 2006 May 3;6:42. PMID: #16672059#