prognostic genetic parameters

Examples

 Deletion of chromosome 11q predicts response to anthracycline-based chemotherapy in early breast cancer. Cancer Res. 2007 Jan 15;67(2):818-26. PMID: 17234794

 Poor survival outcome in breast cancer (gain at 8q24 and loss at 9q13). (11438741)

 Allelic loss in a minimal region on chromosome 16q24 is associated with vitreous seeding of retinoblastoma (17210724)

 Loss of 11q and 16q in Wilms tumors is associated with anaplasia, tumor recurrence, and poor prognosis (17099873)

References

 Wittmann S, Zirn B, Alkassar M, Ambros P, Graf N, Gessler M. Loss of 11q and 16q in Wilms tumors is associated with anaplasia, tumor recurrence, and poor prognosis. Genes Chromosomes Cancer. 2007 Feb;46(2):163-70. PMID: 17099873

 Gratias S, Rieder H, Ullmann R, Klein-Hitpass L, Schneider S, Boloni R, Kappler M, Lohmann DR. Allelic loss in a minimal region on chromosome 16q24 is associated with vitreous seeding of retinoblastoma. Cancer Res. 2007 Jan 1;67(1):408-16. PMID: 17210724

 Deletion of chromosome 11q predicts response to anthracycline-based chemotherapy in early breast cancer. Cancer Res. 2007 Jan 15;67(2):818-26. PMID: 17234794

 Jain AN, Chin K, Borresen-Dale AL, Erikstein BK, Eynstein Lonning P, Kaaresen R, Gray JW. Quantitative analysis of chromosomal CGH in human breast tumors associates copy number abnormalities with p53 status and patient survival. Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7952-7. PMID: 11438741

 Nagy A, Kozma L, Kiss I, Ember I, Takacs I, Hajdu J, Farid NR. Copy number of cancer genes predict tumor grade and survival of pancreatic cancer patients. Anticancer Res. 2001 Mar-Apr;21(2B):1321-5. PMID: 11396207