Colon and rectum

• intramucosal poorly differentiated colorectal carcinoma
  24 August 2016

  References
  Intramucosal poorly differentiated colorectal carcinoma: can it be managed conservatively?
  Shia J, Klimstra DS.
  Am J Surg Pathol. 2008 Oct;32(10):1586-8; author reply 1588-9.
  doi:10.1097/PAS.0b013e31817ec2cd.
  PMID: #18724239#
  Poorly differentiated colorectal carcinoma with invasion restricted to lamina propria (intramucosal carcinoma): a follow-up study of 15 cases. Lewin MR, Fenton H, Burkart AL, Sheridan T, Abu-Alfa AK, Montgomery EA. Am J Surg Pathol. 2007 (...)

• colorectal poorly differentiated neuroendocrine carcinoma
  24 August 2016

  References
  Colorectal poorly differentiated neuroendocrine carcinomas and mixed adenoneuroendocrine carcinomas: insights into the diagnostic immunophenotype, assessment of methylation profile, and search for prognostic markers. La Rosa S, Marando A, Furlan D, Sahnane N, Capella C. Am J Surg Pathol. 2012 Apr;36(4):601-11. doi:10.1097/PAS.0b013e318242e21c.
  PMID: #22314183#

• grading of colorectal adenocarcinoma
  24 August 2016

  References
  Interlaboratory Variability in the Histologic Grading of Colorectal Adenocarcinomas in a Nationwide Cohort. Kuijpers CC, Sluijter CE, von der Thüsen JH, Grünberg K, van Oijen MG, van Diest PJ, Jiwa M, Nagtegaal ID, Overbeek LI, Willems SM. Am J Surg Pathol. 2016 Aug;40(8):1100-8. doi:10.1097/PAS.0000000000000636.
  PMID: #26975039#
  Site-specific tumor grading system in colorectal cancer: multicenter pathologic review of the value of quantifying poorly differentiated clusters. (...)

• poorly differentiated colorectal adenocarcinoma
  24 August 2016

  PDCA
  Open references
  Poorly differentiated cecal adenocarcinoma showing prominent rhabdoid feature combined with appendiceal mucinous cystadenoma: A case report and review of the literature. Cho IJ, Kim SS, Min YD, Noh MW, Hong R. Oncol Lett. 2015 Apr;9(4):1527-1530. PMID: #25788994# (Free)
  References
  Loss of CDX2/CK20 expression is associated with poorly differentiated carcinoma, the CpG island methylator phenotype, and adverse prognosis in microsatellite-unstable colorectal (...)

• colorectal medullary carcinoma
  24 August 2016

  undifferentiated carcinoma, solid type poorly differentiated carcinoma, large cell minimally differentiated carcinoma
  PO
  Definition: WHO recognized subtype of colon carcinoma with solid growth pattern (Hum Pathol 1999;30:843).
  It is relatively rare; usually quoted as < 1% of colorectal neoplasms (Int J Oncol 2010;37:901). Often elderly women (average age 70 years). Usually right sided.
  Strongly associated with high degree of microsatellite instability (MSI), indicative of loss of (...)

• colorectal carcinomas
  24 August 2016

  Definition: Colorectal carcinoma signifies strictly a malignant epithelial tumor of the colon and the rectum. Most of them are colorectal adenocarcinoma /s.
  Types
  colorectal adenocarcinoma colorectal intramucosal carcinoma colorectal mucinous carcinoma colorectal medullary carcinoma colorectal villous carcinoma colorectal signet ring carcinoma
  colorectal adenosquamous carcinoma
  colorectal carcinosarcoma
  colorectal clear cell carcinoma
  colorectal glassy cell carcinoma (...)

• colorectal cancer
  24 August 2016

  Definition: Colorectal cancer signifies strictly a malignant tumor of the colon and the rectum. It is used to signify a colorectal adenocarcinoma.
  See also
  colorectal carcinomas

• ischemic colitis
  24 August 2016

  Images
  Ischemic colitis, typical case https://twitter.com/KUSAURAP/status/766190053185888257
  Ischemic-type injury pattern in colon (secondary to adhesions) https://twitter.com/KristenStashek/status/881918434086440964
  See also
  ischemia ischemic lesions
  colorectal anomalies colonic anomalies colonic mucosal ischemia

• colonic cryptic dysruption
  9 August 2016

  Examples
  ulcerative colitis : ruptured crypt granuloma : mucous extravasation after cryptic dysruption https://twitter.com/DraEosina/status/762961434418483200
  See also
  colonic granuloma
  colonic anomalies
  grnaulomas

• ruptured crypt granuloma
  9 August 2016

  colonic crypt rupture granuloma
  Definition: Crypt-associated giant cells and granulomas can occur in ulcerative colitis and in themselves are unreliable features for the discrimination between Crohn’s disease and ulcerative colitis.
  Isolated giant cells and well-defined epithelioid granulomas distant from crypts do not, as a rule, occur in ulcerative colitis, and hence their presence in a colonoscopic biopsy showing features of chronic inflammatory bowel disease is a strong pointer towards (...)

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