ROCC project

August 2007
Departments of Pathology
Department of Pathology, CHU Sainte-Justine (Jean-Christophe Fournet, Dorothée Bouron-Dal Soglio, Nian Qin Xu)
Department of Pathology, University of Texas (Milton Finegold)
Department of Pathology, Hôpitaux Universitaires de Genève, Switzerland (Anne-Laure Rougemont)
Genome centers
Genome Quebec Innovation Center
See also
ROCC (...)

Rare and orphan children cancers (ROCC) are a group of pediatric cancers that represents about two hundred different tumoral entities. Each tumoral entity has its own way of tumorigenesis involving a specific set of mutated genes (cancer genes), abnormally expressed proteins and deregulated molecular signaling pathways. By their low frequency, very few is known about the molecular tumorigenesis of these models.
We think that this tumoral group represent a still unexploited source of (...)