HER2 testing

ERBB FISH
Images
breast carcinoma : FISH her2 positive / ERBB amplification https://twitter.com/BellaMicheleang/status/799556164128272384
See also
HER2 / ERBB2 HER2 testing

HER2 testing in gastroesophageal adenocarcinoma
News
New guidelines provide recommendations on HER2 testing for patients with gastroesophageal cancers. November 14, 2016
http://www.news-medical.net/news/20161114/New-guidelines-provide-recommendations-on-HER2-testing-for-patients-with-gastroesophageal-cancers.aspx
Open references
Newest recommendations from CAP, ASCP, ASCO on Her2 testing on GI specimens. 2016. (...)

ERBB2 study; HER2 testing
Accurate assessment of HER-2/neu gene status in breast cancer patients has important prognostic and therapeutic implications. Overexpression/gene amplification of HER-2 is associated with a more aggressive clinical course and eligibility for targeted therapy with trastuzumab. A variety of immunohistochemical (IHC) antibodies and in situ hybridisation (ISH) methods have been employed to assess HER-2 status.
Types
HER2 immunochemistry HerceptTest SP3
HER2 (...)

References
Single-Cell Quantitative HER2 Measurement Identifies Heterogeneity and Distinct Subgroups within Traditionally Defined HER2-Positive Patients. Onsum MD et al., The American Journal of Pathology, Volume 183, Issue 5 , Pages 1446-1460, November 2013. doi:10.1016/j.ajpath.2013.07.015

The availability of drugs targeting the EGFR/HER/erbB signaling pathway has created a need for diagnostics that accurately predict treatment responses.
HERmark Breast Cancer Assay precisely quantifies HER2 total protein and HER2 homodimer levels in Formalin Fixed Parrafin Embedded Tissue (FFPE).
The assay performance characteristics are validated according to CLIA standards. HERmark results provide healthcare professionals with additional information for managing breast cancer patients. (...)

Food and Drug Administration (FDA)-approved HER2 FISH pharmDx method

CISH, chromogenic ISH