Molecules

Articles

• lysophosphatidic acid
  31 May 2004

  The bioactive phospholipid lysophosphatidic acid (LPA) stimulates cell proliferation, migration and survival by acting on its cognate G-protein-coupled receptors.
  Aberrant LPA production, receptor expression and signalling probably contribute to cancer initiation, progression and metastasis.
  See also
  lysophospholipids
  References
  Mills GB, Moolenaar WH. The emerging role of lysophosphatidic acid in cancer. Nat Rev Cancer. 2003 Aug;3(8):582-91. PMID: (...)

• dopamine
  9 May 2005

  References
  Lotharius J, Brundin P. Pathogenesis of Parkinson’s disease: dopamine, vesicles and alpha-synuclein. Nat Rev Neurosci. 2002 Dec;3(12):932-42. PMID: #12461550

• gamma-aminobutyric acid
  20 September 2004

  GABA

• nitrogenous base
  29 September 2005

  Definition: A nitrogen-containing molecule having the chemical properties of a base.
  See also
  purine
  pyrimidine

• ADP-ribose
  31 March 2005

  cyclic ADP-ribose

• vitamin-D3
  3 May 2004

  vitamin D, calcitriol

• guanine
  17 October 2005

  Definition: Guanine is a purine base (nitrogenous base) and constituent of nucleotides and as such one member of the base pair G-C (guanine and cytosine).
  Guanine is one of the five main nucleobases found in nucleic acids (e.g., DNA and RNA). Guanine is a purine derivative, and in Watson-Crick base pairing forms three hydrogen bonds with cytosine. Guanine "stacks" vertically with the other nucleobases via aromatic interactions. Guanine is a tautomer (see keto-enol tautomerism). The guanine (...)

• PIP3
  29 October 2003

  Ins(1,4,5)P3, inositol-1,4,5-trisphosphate; phosphatidylinositol 3,4,5-trisphosphate

• GABA signaling
  27 November 2003

  References
  Snead OC 3rd, Gibson KM. Gamma-hydroxybutyric acid. N Engl J Med. 2005 Jun 30;352(26):2721-32. PMID: #15987921#
  Bouche N, Lacombe B, Fromm H. GABA signaling: a conserved and ubiquitous mechanism. Trends Cell Biol. 2003 Dec;13(12):607-610. PMID: #14624837#

• metalloproteins
  11 March 2006

  metalloprotein

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