Home > D. General pathology > Genetic and developmental anomalies > Chromosomal diseases > Constitutional ploidy anomalies > maternal triploidy
maternal triploidy
Wednesday 31 May 2006
Definition: Triploidy resulting in digyny, caused by two haploid sets of maternal chromosomes joined to a haploid paternal set.
Mechanisms
non expulsion of a polar globule
duplication of ovocyte genome
Phenotype
oligohydramnios
severe fetoplacental hypotrophy
- placental hypotrophy
- severe fetal hypotrophy
- dysharmonious fetal hypotrophy (asymetrical fetal hypotrophy)
macrocephaly with ventriculomegaly
micrognathy
macroglossy
3-4 finger syndactyly
genital malformations
fetal adrenal hypoplasia
placental anomalies
- small placental villi
- dystrophic placental villi
- hypovascularized placental villi
- no perivillous trophoblastic hyperplasia
no maternal symptomatology
Diagnosis
triploidy diagnosis
- ploidy assessment by flow cytometry
See also
constitutional triploidies
paternal triploidy
69,XXY triploidy
