kindlin-1
Kindlin-1 is a human homolog of the Caenorhabditis elegans protein UNC-112, a membrane-associated structural/signaling protein that has been implicated in linking the actin cytoskeleton to the extracellular matrix (ECM).
Pathology
Loss-of-function mutations were identified in the KIND1 encoding kindlin-1 in the Kindler’s symdrome