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familial thrombotic thrombocytopenic purpura

MIM.274150 9q34

Thursday 2 February 2006

Etiology

- familial thrombotic thrombocytopenic purpura (TTP) is caused by mutation in the ADAMTS13 gene (MIM.604134) which encodes the von Willebrand factor (VWF) (MIM.193400)-cleaving protease (VWFCP).