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HNF4A

MIM.600281 20q12-q13.1

Pathology

- germline mutations in

  • type I maturity-onset diabetes of the young (MIM.125850)
  • noninsulin-dependent diabetes mellitus (NIDDM) (MIM.125853)
  • HNF4A-associated congenital hyperinsulinism (HNF4A-CHI) (#19566570#)

References

- Neonatal hyperinsulinaemic hypoglycaemia and monogenic diabetes due to a heterozygous mutation of the HNF4A gene. Conn JJ, Simm PJ, Oats JJ, Nankervis AJ, Jacobs SE, Ellard S, Hattersley AT. Aust N Z J Obstet Gynaecol. 2009 Jun;49(3):328-30. PMID: #19566570#