gangliosidoses

Definition: Gangliosidoses are a small group of diseases due to the accumulation of gangliosides. The gangliosidoses are two distinct genetic groups of diseases. Both are autosomal recessive and affect males and females equally. It is a form of lipid storage disorder.

Ganglioside is a compound composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (AKA n-acetylneuraminic acid) linked on the sugar chain.

Types

 GM1-gangliosidosis
 GM2-gangliosidosis

See also

 genetic diseases

• genetic metabolic diseases
  • lysosomal storage diseases

 glycolipids

• glycosphingolipids (ceramide and oligosaccharide)
  • cerebrosides
  • gangliosides
  • globosides